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| Date | Day of Week | Opponent | Home/Away | Time |
| Nov. 11-Dec. 3, 2010 | Monday | Oran Invitational Tournament | Away | TBA |
| December 7, 2010 | Tuesday | Bell City | Home | 6 p.m. |
| December 10, 2010 | Friday | Puxico | Away | 6 p.m. |
| December 17, 2010 | Friday | Scott City | Away | TBA |
| December 27-31, 2010 | Monday | SE Missourian Christmas Tournament | Away | 6 p.m. |
| January 6, 2011 | Thursday | Bernie | Home | 6 p.m. |
| January 7, 2011 | Friday | Portageville | Home | 6 p.m. |
| January 11, 2011 | Tuesday | Chaffee | Away | 6 p.m. |
| January 14, 2011 | Friday | Richland | Away | 6 p.m. |
| January 18, 2011 | Tuesday | Zalma | Away | 6 p.m. |
| January 24-28, 2011 | Monday | SCAA Tournament | Away | TBA |
| February 4, 2011 | Friday | Dexter | Home | 6 p.m. |
| February 8, 2011 | Tuesday | Woodland | Home | 6 p.m. |
| February 11, 2011 | Friday | Delta | Away | 6 p.m. |
| February 12, 2011 | Saturday | South Iron | Away | TBA |
| February 15, 2011 | Tuesday | Oran | Away | 6 p.m. |
| February 17, 2011 | Thursday | Bloomfield | Away | 6 p.m. |
| February 24, 2011 | Thursday | Leopold | Home | 6 p.m. |
Roster
Check back later for the 2010 Advance Boys Basketball roster.