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Schedule
| Date | Day of Week | Opponent | Home/Away | Time |
| August 23, 2010 | Monday | Doniphan | Away | 3 p.m. |
| August 24, 2010 | Tuesday | Thayer | Away | 4 p.m. |
| August 26, 2010 | Thursday | Mt. View | Home | 4:30 p.m. |
| August 31, 2010 | Tuesday | East Carter | Home | 3:30 p.m. |
| September 2, 2010 | Thursday | Alton | Away | 4:30 p.m. |
| September 3, 2010 | Friday | Couch | Home | 4 p.m. |
| September 7, 2010 | Tuesday | East Carter | Away | 4 p.m. |
| September 14, 2010 | Tuesday | Clearwater | Home | 4 p.m. |
| September 16, 2010 | Thursday | Winona | Away | 4 p.m. |
| September 17, 2010 | Friday | Neelyville | Away | 4:30 p.m. |
| September 20, 2010 | Monday | Winona | Home | 4 p.m. |
| September 23, 2010 | Thursday | Greenville | Away | 4:30 p.m. |
| September 25, 2010 | Saturday | Current River Classic | Home | TBA |
| September 27, 2010 | Monday | Alton | Home | 4 p.m. |
| September 28, 2010 | Tuesday | Willow Springs | Home | 4:30 p.m. |
| October 4, 2010 | Monday | Twin Rivers | Home | 4 p.m. |
Roster
Check back later for the 2010 Van Buren softball roster.