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Schedule
| Date | Day of Week | Opponent | Home/Away | Time |
| March 21, 2011 | Monday | Holcomb | Home | 4:30 p.m. |
| March 22, 2011 | Tuesday | Campbell | Away | 4:30 p.m. |
| March 28, 2011 | Monday | Delta C-7 | Away | 4:30 p.m. |
| March 29, 2011 | Tuesday | Senath | Away | 4:30 p.m. |
| March 31, 2011 | Thursday | Caruthersville | Away | 4:30 p.m. |
| April 5, 2011 | Tuesday | Hayti | Away | 4:30 p.m. |
| April 11, 2011 | Monday | Gideon | Home | 4:30 p.m. |
| April 12, 2011 | Tuesday | Malden | Away | 4:30 p.m. |
| April 14, 2011 | Thursday | Delta C-7 | Home | 4:30 p.m. |
| April 18, 2011 | Monday | East Prairie | Away | 4:30 p.m. |
| April 21, 2011 | Thursday | Kennett | Home | 4:30 p.m. |
| April 25, 2011 | Monday | Senath | Home | 4:30 p.m. |
| April 26, 2011 | Tuesday | Kennett | Away | 4:30 p.m. |
| May 2, 2011 | Monday | Portageville | Away | 4:30 p.m. |
| May 3, 2011 | Tuesday | New Madrid | Home | 4:30 p.m. |
| May 5, 2011 | Thursday | Malden | Home | 4:15 p.m. |
| May 6, 2011 | Friday | North Pemiscot | Away | 4:30 p.m. |
| May 9-13, 2011 | Mon.-Fri. | Bootheel Conference Tournament | Away | TBA |
Roster
Check back later for the 2011 South Pemiscot Softball roster.